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PROPECIA (finasteride), a synthetic
4-azasteroid compound, is a specific inhibitor of
steroid Type II 5a-reductase, an
intracellular enzyme that converts the androgen
testosterone into 5a-dihydrotestosterone (DHT).
Finasteride is
4-azaandrost-1-ene-17-carboxamide,N-(1,1-dimethylethyl)-3-oxo-,(5a,17b)-. The empirical formula of finasteride is
C23H36N2O2
and its molecular weight is 372.55. Its structural
formula is:
Finasteride is a white crystalline powder with a
melting point near 250°C. It is freely soluble in
chloroform and in lower alcohol solvents but is
practically insoluble in water.
PROPECIA tablets for oral administration are
film-coated tablets that contain 1 mg of
finasteride and the following inactive ingredients:
lactose monohydrate, microcrystalline cellulose,
pregelatinized starch, sodium starch glycolate, docusate
sodium, magnesium stearate, hydroxypropyl
methylcellulose 2910, hydroxypropyl cellulose, titanium
dioxide, talc, yellow ferric oxide, and red ferric
oxide.
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Propecia Description
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